Chicken Liver Microsomes

Details

Chicken Liver Microsomes are subcellular fractions enriched with intact drug-metabolizing enzymes, including cytochrome P450 (CYP) enzymes, UDP-glucuronosyltransferases (UGTs), and flavin-containing monooxygenases (FMOs).

They are essential in vitro tools for studying metabolic stability, drug–drug interactions, toxic metabolite formation, and interspecies differences.

MileCell provides high-quality liver microsomes from multiple species, including mouse, rat, dog, and monkey.

Features and Benefits

*Quality Assurance: All batches undergo comprehensive quality control procedures to ensure product integrity and batch-to-batch consistency.

*Comprehensive Characterization: Key CYP and Phase II enzyme activities are characterized to ensure consistent metabolic performance and specificity.

*Scalable Production: Large lots derived from pooled liver subcellular fractions minimize lot-to-lot variation and support long-term study continuity.

*Well-Stocked Inventory: Fresh, high-quality microsomes are readily available.

*Customizable Options: Gender, species, vial size, and batch size available upon request.

Quality

This product is intended for in-vitro research and manufacturing applications only. All biological samples supplied by MileCell, as well as any materials derived from them, are strictly for in-vitro research use. They are not approved or intended for use as source material in clinical therapies.

Microsomes are provided as a suspension at a concentration of 20 mg/mL in a 250 mM sucrose buffer. Each vial contains a total volume of 0.5 mL. Every production lot is tested for enzymatic activity and metabolic stability to ensure consistent performance.