2025.06.16
Struggling with variable metabolic data? MileCell Bio’s Liver Microsomes deliver unmatched lot-to-lot consistency and superior metabolic activity, enabling reliable ADME predictions for drug discovery.
l Minimized Variability: Large pooled lots (>300 vials/lot) from male/female donors ensure reproducible inter-lot metabolic activity.
l Enhanced Metabolic Performance: Characterization of key CYP, FMO, and UGT enzymes guarantees exceptional metabolic specificity (Fig 7).
l Species-Specific Insights: Mouse, rat, dog, monkey & more – ideal for cross-species metabolism comparisons.
l Safety Compliance: Rigorous serological testing and ethical sourcing.
In-house validation demonstrates MileCell’s microsomes outperform competitors in intrinsic clearance (Clint):
· Higher metabolic activity for 7 compounds vs. Brand A/B (Fig 7).
· Optimized for stability studies: Ideal for predicting in vivo clearance and metabolite profiling.
Need species-specific or gender-pooled microsomes? MileCell offers tailored subcellular fractions to meet unique research demands.
Tags:
#ADME #DrugMetabolism #LiverMicrosomes #DrugDiscovery #PreclinicalResearch #Biotech #MetabolicStability #CYP450
Elevate Your Research:
Explore our Liver Microsomes: www.milecell-bio.com
Contact: Info@milecell-bio.com
